{"id":67125,"date":"2024-02-22T14:56:41","date_gmt":"2024-02-22T07:56:41","guid":{"rendered":"https:\/\/hmm88i.com\/drug\/?post_type=product&#038;p=67125"},"modified":"2025-07-24T13:43:22","modified_gmt":"2025-07-24T06:43:22","slug":"gliptinestad-25","status":"publish","type":"product","link":"https:\/\/hmm88i.com\/drug\/gliptinestad-25\/","title":{"rendered":"Gliptinestad 25"},"content":{"rendered":"<p><b>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m <a href=\"https:\/\/hmm88i.com\/drug\/gliptinestad-25\/\">thu\u1ed1c Gliptinestad 25<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm, hi\u1ec7n \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam.\u00a0<\/b><\/p>\n<p>&nbsp;<\/p>\n<h2><span style=\"font-weight: 400\">Gliptinestad 25 l\u00e0 thu\u1ed1c g\u00ec?<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u00e0nh ph\u1ea7n<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Thu\u1ed1c Gliptinestad 25<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sitagliptin 25mg<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Tr\u00ecnh b\u00e0y<\/span><\/h3>\n<p><span style=\"font-weight: 400\">S\u0110K: \u0110ang c\u1eadp nh\u1eadt<\/span><\/p>\n<p><span style=\"font-weight: 400\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 28 vi\u00ean<\/span><\/p>\n<p><span style=\"font-weight: 400\">Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Gliptinestad 25<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/span><\/h3>\n<p><span style=\"font-weight: 400\"><strong>Sitagliptin<\/strong>:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u1ee8c ch\u1ebf dipeptidyl peptidase-4 (DPP-4) &#8211; enzym l\u00e0m b\u1ea5t ho\u1ea1t c\u00e1c hormone k\u00edch th\u00edch ti\u1ebft Insulin.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">T\u0103ng n\u1ed3ng \u0111\u1ed9 GIP v\u00e0 GLP-1 &#8211; k\u00edch th\u00edch s\u1ea3n sinh Insulin v\u00e0 gi\u1ea3m s\u1ea3n xu\u1ea5t glucose.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Hi\u1ec7u qu\u1ea3 trong vi\u1ec7c h\u1ea1 glucose huy\u1ebft l\u00fac \u0111\u00f3i v\u00e0 sau \u0103n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u00cdt g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft qu\u00e1 m\u1ee9c v\u00e0 kh\u00f4ng l\u00e0m \u1ea3nh h\u01b0\u1edfng kh\u1ed1i l\u01b0\u1ee3ng c\u01a1 th\u1ec3.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400\">H\u1ea5p thu:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sitagliptin \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua ti\u00eau h\u00f3a.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u1ea3 d\u1ee5ng sinh h\u1ecdc hay t\u1ef7 l\u1ec7 Sitagliptin h\u1ea5p thu v\u00e0o c\u01a1 th\u1ec3 \u0111\u1ea1t 87%.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u0110\u1ec9nh n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u \u0111\u1ea1t sau 3h u\u1ed1ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Qu\u00e1 tr\u00ecnh h\u1ea5p thu kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi vi\u1ec7c \u0103n u\u1ed1ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u1eaft \u0111\u1ea7u c\u00f3 hi\u1ec7u qu\u1ea3 sau 1h u\u1ed1ng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf DPP-4 \u0111\u1ea1t 80% v\u00e0 k\u00e9o d\u00e0i 12-24 gi\u1edd.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Ph\u00e2n b\u1ed1:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sitagliptin ph\u00e2n b\u1ed1 r\u1ed9ng kh\u1eafp c\u01a1 th\u1ec3 v\u1edbi th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 198 l\u00edt.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">38% c\u1ee7a Sitagliptin k\u1ebft h\u1ee3p v\u1edbi protein trong huy\u1ebft t\u01b0\u01a1ng.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sitagliptin \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu b\u1edfi h\u1ec7 th\u1ed1ng cytochrom P450 (CYP), bao g\u1ed3m isoenzym CYP3A4 v\u00e0 CYP2C8.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Chuy\u1ec3n h\u00f3a s\u1ea3n xu\u1ea5t c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Th\u1ea3i tr\u1eeb:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">87% gi\u1eef nguy\u00ean \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i qua n\u01b0\u1edbc ti\u1ec3u.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ea7n c\u00f2n l\u1ea1i (kho\u1ea3ng 13%) \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua ph\u00e2n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sitagliptin \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua \u1ed1ng th\u1eadn theo ph\u01b0\u01a1ng th\u1ee9c v\u1eadn chuy\u1ec3n t\u00edch c\u1ef1c.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1eddi gian c\u1ea7n \u0111\u1ec3 m\u1ed9t n\u1eeda l\u01b0\u1ee3ng Sitagliptin \u0111\u01b0\u1ee3c th\u1ea3i lo\u1ea1i kh\u1ecfi c\u01a1 th\u1ec3 l\u00e0 12,4 gi\u1edd.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Gliptinestad 25 Stella \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">\u0110i\u1ec1u ch\u1ec9nh \u0111\u01b0\u1eddng huy\u1ebft \u1edf ng\u01b0\u1eddi b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng t\u00fdp 2:<\/span><\/p>\n<p><span style=\"font-weight: 400\">Li\u1ec7u ph\u00e1p \u0111\u01a1n \u0111\u1ed9c:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u00c1p d\u1ee5ng khi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng &amp; t\u1eadp luy\u1ec7n kh\u00f4ng hi\u1ec7u qu\u1ea3 ho\u1eb7c kh\u00f4ng th\u1ec3\/kh\u00f4ng dung n\u1ea1p metformin.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Tr\u1ecb li\u1ec7u k\u00e9p:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Metformin: S\u1eed d\u1ee5ng khi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, t\u1eadp luy\u1ec7n &amp; Metformin \u0111\u01a1n \u0111\u1ed9c kh\u00f4ng hi\u1ec7u qu\u1ea3.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sulphonylurea: D\u00f9ng khi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, t\u1eadp luy\u1ec7n &amp; Sulfonylurea \u0111\u01a1n \u0111\u1ed9c (li\u1ec1u t\u1ed1i \u0111a) kh\u00f4ng hi\u1ec7u qu\u1ea3 v\u00e0 kh\u00f4ng th\u1ec3\/kh\u00f4ng dung n\u1ea1p metformin.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u1ea5t ch\u1ee7 v\u1eadn PPAR\u03b3 (thiazolidinedione): D\u00f9ng khi ph\u00f9 h\u1ee3p v\u00e0 ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, t\u1eadp luy\u1ec7n &amp; ch\u1ea5t ch\u1ee7 v\u1eadn PPAR\u03b3 \u0111\u01a1n \u0111\u1ed9c kh\u00f4ng hi\u1ec7u qu\u1ea3.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Tr\u1ecb li\u1ec7u 3 thu\u1ed1c:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Sulphonylurea &amp; Metformin: D\u00f9ng khi 2 thu\u1ed1c n\u00e0y c\u00f9ng ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng &amp; t\u1eadp luy\u1ec7n kh\u00f4ng hi\u1ec7u qu\u1ea3.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ch\u1ea5t ch\u1ee7 v\u1eadn PPAR\u03b3 &amp; Metformin: D\u00f9ng khi ph\u00f9 h\u1ee3p v\u00e0 2 thu\u1ed1c n\u00e0y c\u00f9ng ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng &amp; t\u1eadp luy\u1ec7n kh\u00f4ng hi\u1ec7u qu\u1ea3.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">L\u1ef1a ch\u1ecdn k\u1ebft h\u1ee3p Sitagliptin v\u1edbi insulin (c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng metformin) \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc khi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, t\u1eadp luy\u1ec7n &amp; insulin (li\u1ec1u \u1ed5n \u0111\u1ecbnh) kh\u00f4ng \u0111\u1ee7 \u0111\u1ec3 ki\u1ec3m so\u00e1t l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Gliptinestad 25<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 47.0111%;text-align: center\"><span style=\"font-weight: 400\">\u0110\u1ed1i t\u01b0\u1ee3ng<\/span><\/td>\n<td style=\"width: 52.9151%;text-align: center\"><span style=\"font-weight: 400\">Li\u1ec1u d\u00f9ng<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\"><span style=\"font-weight: 400\">Ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh<\/span><\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">4 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\"><span style=\"font-weight: 400\">K\u1ebft h\u1ee3p v\u1edbi Metformin v\u00e0\/ho\u1eb7c ch\u1ea5t ch\u1ee7 v\u1eadn PPAR\u03b3<\/span><\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">Duy tr\u00ec li\u1ec1u Metformin\/PPAR\u03b3 v\u00e0 d\u00f9ng \u0111\u1ed3ng th\u1eddi Gliptinestad<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\"><span style=\"font-weight: 400\">K\u1ebft h\u1ee3p v\u1edbi Sulphonylurea ho\u1eb7c insulin<\/span><\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">Xem x\u00e9t gi\u1ea3m li\u1ec1u Sulphonylurea\/Insulin \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\"><span style=\"font-weight: 400\">Ng\u01b0\u1eddi cao tu\u1ed5i<\/span><\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\"><span style=\"font-weight: 400\">Tr\u1ebb em d\u01b0\u1edbi 17 tu\u1ed5i<\/span><\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">Kh\u00f4ng d\u00f9ng<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 99.9262%\" colspan=\"2\"><span style=\"font-weight: 400\">Suy th\u1eadn<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">GFR \u2265 60 \u0111\u1ebfn &lt; 90 ml\/ph\u00fat<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">4 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">GFR \u2265 45 \u0111\u1ebfn &lt; 60 ml\/ph\u00fat<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">4 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">GFR \u2265 30 \u0111\u1ebfn &lt; 45 ml\/ph\u00fat<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">2 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">GFR \u2265 15 \u0111\u1ebfn &lt; 30 ml\/ph\u00fat ho\u1eb7c ESRD (GFR &lt; 15 ml\/ph\u00fat)<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">1 vi\u00ean\/l\u1ea7n\/ng\u00e0y<\/span><\/p>\n<p><span style=\"font-weight: 400\">D\u00f9ng m\u1ecdi l\u00fac, kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1eddi gian th\u1ea9m t\u00e1ch m\u00e1u.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 99.9262%\" colspan=\"2\"><span style=\"font-weight: 400\">Suy gan<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nh\u1eb9 \u0111\u1ebfn v\u1eeba<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 47.0111%\">\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">N\u1eb7ng<\/span><\/li>\n<\/ul>\n<\/td>\n<td style=\"width: 52.9151%\"><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng, ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">C\u00e1ch d\u00f9ng<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gliptinestad 25 c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Gliptinestad 25 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">D\u1ecb \u1ee9ng v\u1edbi Sitagliptin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a <strong>thu\u1ed1c Gliptinestad 25 Stella.<\/strong><\/span><\/p>\n<p><span style=\"font-weight: 400\">\u0110\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 1.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Ng\u01b0\u1eddi c\u00f3 nhi\u1ec5m toan ceton do ti\u1ec3u \u0111\u01b0\u1eddng.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Vi\u00eam t\u1ee5y c\u1ea5p.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Gliptinestad 25<\/span><\/h2>\n<h3><span style=\"font-weight: 400\">Th\u1eadn tr\u1ecdng<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft khi d\u00f9ng k\u1ebft h\u1ee3p v\u1edbi insulin ho\u1eb7c sulphonylurea (c\u00e2n nh\u1eafc gi\u1ea3m li\u1ec1u).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">C\u1ea7n gi\u1ea3m li\u1ec1u Sitagliptin \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn (GFR &lt; 45 ml\/ph\u00fat) ho\u1eb7c b\u1ec7nh th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i (ESRD) \u0111ang th\u1ea9m t\u00e1ch m\u00e1u ho\u1eb7c th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn (ng\u01b0ng d\u00f9ng thu\u1ed1c, \u0111\u00e1nh gi\u00e1 nguy\u00ean nh\u00e2n, thay th\u1ebf c\u00e1ch tr\u1ecb li\u1ec7u).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u1ec7nh da b\u1ecdng n\u01b0\u1edbc pemphigoid (d\u1eebng thu\u1ed1c).<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Th\u01b0\u1eddng g\u1eb7p<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gi\u1ea3m \u0111\u01b0\u1eddng huy\u1ebft<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nh\u1ee9c \u0111\u1ea7u.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">\u00cdt g\u1eb7p<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Hoa m\u1eaft<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">B\u00ed \u0111\u1ea1i ti\u1ec7n<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ng\u1ee9a ng\u00e1y<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 16.5314%;text-align: center\"><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><\/td>\n<td style=\"width: 83.3948%;text-align: center\"><span style=\"font-weight: 400\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 99.9262%\" colspan=\"2\"><span style=\"font-weight: 400\">Thu\u1ed1c t\u00e1c \u0111\u1ed9ng l\u00ean Sitagliptin<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.5314%\"><span style=\"font-weight: 400\">Ch\u1ea5t \u1ee9c ch\u1ebf m\u1ea1nh CYP3A4<\/span><\/td>\n<td style=\"width: 83.3948%\"><span style=\"font-weight: 400\">C\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a Sitagliptin \u1edf ng\u01b0\u1eddi b\u1ec7nh suy th\u1eadn n\u1eb7ng ho\u1eb7c b\u1ec7nh th\u1eadn giai \u0111o\u1ea1n cu\u1ed1i.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.5314%\"><span style=\"font-weight: 400\">Probencid<\/span><\/td>\n<td style=\"width: 83.3948%\"><span style=\"font-weight: 400\">\u1ee8c ch\u1ebf qu\u00e1 tr\u00ecnh v\u1eadn chuy\u1ec3n Sitagliptin qua h\u1ec7 OAT3, ch\u01b0a c\u00f3 \u1ea3nh h\u01b0\u1edfng quan tr\u1ecdng trong th\u1ef1c t\u1ebf l\u00e2m s\u00e0ng.<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 99.9262%\" colspan=\"2\"><span style=\"font-weight: 400\">Sitagliptin t\u00e1c \u0111\u1ed9ng l\u00ean c\u00e1c thu\u1ed1c kh\u00e1c<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.5314%\"><span style=\"font-weight: 400\">Digoxin<\/span><\/td>\n<td style=\"width: 83.3948%\"><span style=\"font-weight: 400\">T\u0103ng n\u1ed3ng \u0111\u1ed9 Digoxin trong huy\u1ebft t\u01b0\u01a1ng. Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u v\u1edbi Digoxin, nh\u01b0ng c\u1ea7n th\u1eadn tr\u1ecdng \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 ng\u1ed9 \u0111\u1ed9c.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Kh\u00f4ng s\u1eed d\u1ee5ng Gliptinestad 25.<\/span><\/p>\n<h3><span style=\"font-weight: 400\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/span><\/h3>\n<p><span style=\"font-weight: 400\">Tri\u1ec7u ch\u1ee9ng:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Li\u1ec1u \u0111\u01a1n l\u1ebb \u0111\u1ebfn 800mg: Kh\u00f4ng c\u00f3 bi\u1ec3u hi\u1ec7n b\u1ea5t th\u01b0\u1eddng.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Li\u1ec1u 869mg: K\u00e9o d\u00e0i kho\u1ea3ng QTe m\u1ed9t c\u00e1ch nh\u1eb9 (kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ee9c kh\u1ecfe).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Li\u1ec1u cao h\u01a1n 800mg: Ch\u01b0a ghi nh\u1eadn th\u00f4ng tin.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">X\u1eed tr\u00ed<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Lo\u1ea1i b\u1ecf ph\u1ea7n thu\u1ed1c ch\u01b0a \u0111\u01b0\u1ee3c h\u1ea5p thu kh\u1ecfi h\u1ec7 ti\u00eau h\u00f3a.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Theo d\u00f5i t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe (bao g\u1ed3m \u0111i\u1ec7n t\u00e2m \u0111\u1ed3).<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">L\u1ecdc m\u00e1u: Lo\u1ea1i b\u1ecf 13,5% l\u01b0\u1ee3ng sitagliptin \u0111\u00e3 s\u1eed d\u1ee5ng sau 3-4h.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">L\u1ecdc m\u00e1u k\u00e9o d\u00e0i: \u00c1p d\u1ee5ng t\u00f9y theo t\u00ecnh tr\u1ea1ng b\u1ec7nh nh\u00e2n.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c: Hi\u1ec7u qu\u1ea3 ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400\">Thu\u1ed1c Gliptinestad 25 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/span><\/h2>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c Gliptinestad 25 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Gliptinestad 25 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Gliptinestad 25 nh\u01b0:\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c <\/span><a href=\"https:\/\/www.hmm88i.com\/drug\/januvia\"><span style=\"font-weight: 400\">Januvia<\/span><\/a><span style=\"font-weight: 400\"> c\u00f3 gi\u00e1 525.000\u0111\/h\u1ed9p do C\u00f4ng ty Merck Sharp &amp; Dohme (Italia) S.P.A &#8211; \u00dd s\u1ea3n xu\u1ea5t. Thu\u1ed1c Januvia \u0111\u01b0\u1ee3c d\u00f9ng cho c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng trong giai \u0111o\u1ea1n \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp II, v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng h\u1ed7 tr\u1ee3 trong vi\u1ec7c \u0103n u\u1ed1ng., v\u1eadn \u0111\u1ed9ng v\u00e0 ki\u1ebfm so\u00e1t l\u1ef1\u1ee3ng \u0111\u01b0\u1eddng huy\u1ebft trong c\u01a1 th\u1ec3.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Thu\u1ed1c<\/span><a href=\"https:\/\/www.hmm88i.com\/drug\/zlatko-100\"><span style=\"font-weight: 400\"> Zlatko 100<\/span><\/a><span style=\"font-weight: 400\"> c\u00f3 gi\u00e1 495.000\u0111\/h\u1ed9p do C\u00f4ng ty CP D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa (DAVIPHARM) s\u1ea3n xu\u1ea5t. Thu\u1ed1c Zlatko 100 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 2; k\u1ebft h\u1ee3p v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, luy\u1ec7n t\u1eadp th\u1ec3 d\u1ee5c v\u00e0 s\u1eed d\u1ee5ng c\u00f9ng c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c \u0111\u1ec3 t\u0103ng hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n<h2><span style=\"font-weight: 400\">T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c Gliptinestad 25?<\/span><\/h2>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 49.9631%;text-align: center\"><span style=\"font-weight: 400\">\u01afu \u0111i\u1ec3m<\/span><\/td>\n<td style=\"width: 49.9631%;text-align: center\"><span style=\"font-weight: 400\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 49.9631%\"><span style=\"font-weight: 400\">Gi\u00fap ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft hi\u1ec7u qu\u1ea3 \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng lo\u1ea1i 2.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Gi\u1ea3m nguy c\u01a1 bi\u1ebfn ch\u1ee9ng tim m\u1ea1ch.<\/span><\/p>\n<p><span style=\"font-weight: 400\">An to\u00e0n v\u00e0 dung n\u1ea1p t\u1ed1t.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Gliptinestad 25 kh\u00f4ng g\u00e2y l\u00ean c\u00e2n.\u00a0<\/span><\/td>\n<td style=\"width: 49.9631%\"><span style=\"font-weight: 400\">Vi\u1ec7c s\u1eed d\u1ee5ng Sitagliptine c\u1ea7n \u0111\u01b0\u1ee3c b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh v\u00e0 theo d\u00f5i c\u1ee5 th\u1ec3.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-weight: 400\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Antonio Ceriello, Liberata Sportiello, Concetta Rafaniello, Francesco Rossi. (Th\u00e1ng 9 n\u0103m 2014). <\/span><i><span style=\"font-weight: 400\">DPP-4 inhibitors: pharmacological differences and their clinical implications<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 22 th\u00e1ng 2 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25171159\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25171159\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gary A Herman, Cathy Stevens, Kristien Van Dyck, Arthur Bergman, Bingming Yi, Marina De Smet, Karen Snyder, Deborah Hilliard, Michael Tanen, Wesley Tanaka, Amy Q Wang, Wei Zeng, Donald Musson, Gregory Winchell, Michael J Davies, Steven Ramael, Keith M Gottesdiener, John A Wagner. (Th\u00e1ng 12 n\u0103m 2005). <\/span><i><span style=\"font-weight: 400\">Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses<\/span><\/i><span style=\"font-weight: 400\">. Truy c\u1eadp ng\u00e0y 22 th\u00e1ng 2 n\u0103m 2024, t\u1eeb <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16338283\/\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16338283\/<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Gliptinestad 25 l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng t\u00fdp 2 thu\u1ed9c nh\u00f3m thu\u1ed1c g\u1ecdi l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf dipeptidyl peptidase-4 (DPP-4).<\/p>\n","protected":false},"author":1,"featured_media":67111,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-67125","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product\/67125","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/comments?post=67125"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/media\/67111"}],"wp:attachment":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/media?parent=67125"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product_cat?post=67125"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product_tag?post=67125"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}