{"id":41677,"date":"2023-09-11T12:13:32","date_gmt":"2023-09-11T05:13:32","guid":{"rendered":"https:\/\/hmm88i.com\/drug\/?post_type=product&#038;p=41677"},"modified":"2025-07-24T14:03:50","modified_gmt":"2025-07-24T07:03:50","slug":"ckdcipol-n-100mg","status":"publish","type":"product","link":"https:\/\/hmm88i.com\/drug\/ckdcipol-n-100mg\/","title":{"rendered":"CKDCIPOL-N 100mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/hmm88i.com\/drug\/ckdcipol-n-100mg\/\">CKDCIPOL-N 100mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi SUHEUNG CO, LTD- H\u00e0n Qu\u1ed1c, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18192-14<\/strong><\/p>\n<h2>CKDCIPOL-N 100mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean <strong>CKDCIPOL-N 100mg<\/strong> ch\u1ee9a:<br \/>\nHo\u1ea1t ch\u1ea5t: Cyclosporin 100mg d\u1ea1ng vi nh\u0169 t\u01b0\u01a1ng.<br \/>\nT\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<br \/>\nD\u1ea1ng b\u00e0o ch\u1ebf: vi\u00ean nang m\u1ec1m.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18192-14.<br \/>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 5 vi\u00ean.<br \/>\nXu\u1ea5t x\u1ee9: H\u00e0n Qu\u1ed1c.<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Ho\u1ea1t ch\u1ea5t Cyclosporin l\u00e0 m\u1ed9t s\u1ea3n ph\u1ea9m do n\u1ea5m chuy\u1ec3n h\u00f3a th\u00e0nh, c\u00f3 ho\u1ea1t t\u00ednh gi\u1ea3m mi\u1ec5n d\u1ecbch m\u1ea1nh. Cyclosporin \u0111\u1ed9c h\u1ea1i r\u00f5 r\u1ec7t \u0111\u1ed1i v\u1edbi th\u1eadn nh\u01b0ng h\u1ea7u nh\u01b0 kh\u00f4ng \u0111\u1ed9c h\u1ea1i v\u1edbi t\u1ee7y. Ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong gh\u00e9p c\u00e1c m\u00f4 v\u00e0 c\u01a1 quan v\u1edbi m\u1ee5c \u0111\u00edch d\u1ef1 ph\u00f2ng b\u1ec7nh do m\u1ea3nh gh\u00e9p g\u00e2y ra cho ng\u01b0\u1eddi nh\u1eadn v\u00e0 d\u1ef1 ph\u00f2ng lo\u1ea1i b\u1ecf m\u1ea3nh gh\u00e9p sau khi gh\u00e9p c\u00e1c m\u00f4 c\u01a1 quan nh\u01b0: t\u1ee7y x\u01b0\u01a1ng, th\u1eadn, gan, t\u1ee5y, tim v\u00e0 tim \u2013 ph\u1ed5i.<\/p>\n<p>Cyclosporin ho\u1ea1t \u0111\u1ed9ng theo 2 c\u01a1 ch\u1ebf:<br \/>\nT\u00e1c \u0111\u1ed9ng \u1edf pha G0 v\u00e0 G1 c\u1ee7a chu k\u1ef3 t\u1ebf b\u00e0o lympho v\u1edbi kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf \u0111\u1eb7c hi\u1ec7u, c\u00f3 h\u1ed3i ph\u1ee5c c\u00e1c t\u1ebf b\u00e0o lympho c\u00f3 kh\u1ea3 n\u0103ng mi\u1ec5n d\u1ecbch.<br \/>\n\u1ee8c ch\u1ebf gi\u1ea3i ph\u00f3ng v\u00e0 s\u1ea3n xu\u1ea5t c\u00e1c lymphokin (ch\u1ee7 y\u1ebfu interleukin \u2013 2).<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Sau khi u\u1ed1ng 1,3 -4 gi\u1edd thu\u1ed1c \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng.<br \/>\n\u0110\u1eb7c \u0111i\u1ec3m v\u1ec1 h\u1ea5p thu c\u1ee7a d\u1ea1ng u\u1ed1ng v\u00e0 d\u1ea1ng vi nh\u0169 t\u01b0\u01a1ng \u0111\u01b0\u1ee3c tr\u00ecnh b\u00e0y nh\u01b0 sau:<\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 106px;\">\n<tbody>\n<tr style=\"height: 21px;\">\n<td style=\"width: 50%; height: 21px;\">Cyclosporin<\/td>\n<td style=\"width: 50%; height: 21px;\">\u0110\u1eb7c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr style=\"height: 64px;\">\n<td style=\"width: 50%; height: 64px;\">D\u1ea1ng u\u1ed1ng<\/td>\n<td style=\"width: 50%; height: 64px;\">H\u1ea5p thu ch\u1eadm v\u00e0 kh\u00f4ng ho\u00e0n to\u00e0n. Sinh kh\u1ea3 d\u1ee5ng ch\u1ec9 kho\u1ea3ng 20 \u2013 50%.<br \/>\nTh\u1ee9c \u0103n c\u00f3 nhi\u1ec1u ch\u1ea5t b\u00e9o l\u00e0m ch\u1eadm h\u1ea5p thu.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 50%; height: 21px;\">D\u1ea1ng vi nh\u0169 t\u01b0\u01a1ng<\/td>\n<td style=\"width: 50%; height: 21px;\">Sinh kh\u1ea3 d\u1ee5ng l\u1edbn h\u01a1n.<br \/>\nTh\u1ee9c \u0103n ch\u1ee9a nhi\u1ec1u ch\u1ea5t b\u00e9o kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ea5p thu.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 bi\u1ec3u ki\u1ebfn c\u1ee7a Cyclosporin kh\u00e1 l\u1edbn (13 l\u00edt\/kg). Trong m\u00e1u to\u00e0n ph\u1ea7n c\u00f3:<\/p>\n<ul>\n<li>50 \u2013 60% cyclosporin t\u00edch l\u0169y \u1edf h\u1ed3ng c\u1ea7u.<\/li>\n<li>10 \u2013 20% l\u01b0\u1ee3ng thu\u1ed1c k\u1ebft h\u1ee3p v\u1edbi b\u1ea1ch c\u1ea7u trong tu\u1ea7n ho\u00e0n.<\/li>\n<li>C\u00f2n l\u1ea1i k\u1ebft h\u1ee3p v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<\/ul>\n<p>Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 6 gi\u1edd. Ph\u1ea7n l\u1edbn Cyclosporin chuy\u1ec3n h\u00f3a \u1edf gan th\u00e0nh h\u01a1n 30 s\u1ea3n ph\u1ea9m chuy\u1ec3n h\u00f3a. Ch\u1ec9 kho\u1ea3ng 6% Cyclosporin v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u c\u00f2n l\u1ea1i ch\u1ee7 y\u1ebfu b\u00e0i ti\u1ebft qua m\u1eadt v\u00e0o ph\u00e2n.<\/p>\n<h2>Thu\u1ed1c CKDCIPOL-N 100mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 25.831%; text-align: center;\" colspan=\"2\">Ch\u1ec9 \u0111\u1ecbnh<\/td>\n<td style=\"width: 74.1689%; text-align: center;\">Tr\u01b0\u1eddng h\u1ee3p c\u1ee5 th\u1ec3<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 10.8265%;\" rowspan=\"2\">Trong gh\u00e9p t\u1ea1ng<\/td>\n<td style=\"width: 15.0045%;\">Gh\u00e9p t\u1ea1ng \u0111\u1eb7c<\/td>\n<td style=\"width: 74.1689%;\">Sau khi gh\u00e9p c\u00f9ng lo\u1ea1i c\u00e1c t\u1ea1ng (th\u1eadn, gan, tim, ph\u1ed5i, tim-ph\u1ed5i ho\u1eb7c t\u1ee5y-t\u1ea1ng) \u0111\u1ec3 ng\u0103n ng\u1eeba th\u1ea3i b\u1ecf m\u1ea3nh gh\u00e9p.<br \/>\nD\u00f9ng cho b\u1ec7nh nh\u00e2n \u0111\u00e3 s\u1eed d\u1ee5ng nh\u1eefng thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch kh\u00e1c \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb th\u1ea3i lo\u1ea1i m\u1ea3nh gh\u00e9p.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.0045%;\">Gh\u00e9p t\u1ee7y x\u01b0\u01a1ng<\/td>\n<td style=\"width: 74.1689%;\">D\u00f9ng sau khi gh\u00e9p t\u1ee7y x\u01b0\u01a1ng \u0111\u1ec3 ng\u0103n ng\u1eeba s\u1ef1 th\u1ea3i m\u1ea3nh gh\u00e9p.<br \/>\nB\u1ec7nh GVHD-m\u1ea3nh gh\u00e9p ch\u1ed1ng l\u1ea1i v\u1eadt ch\u1ee7.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 10.8265%;\" rowspan=\"5\">Trong c\u00e1c b\u1ec7nh kh\u00f4ng gh\u00e9p t\u1ea1ng<\/td>\n<td style=\"width: 15.0045%;\">Vi\u00eam m\u00e0ng b\u1ed3 \u0111\u00e0o n\u1ed9i sinh<\/td>\n<td style=\"width: 74.1689%;\">\u0110i\u1ec1u tr\u1ecb vi\u00eam m\u00e0ng b\u1ed3 \u0111\u00e0o trung gian ho\u1eb7c \u1edf ph\u00eda sau \u0111e d\u1ecda th\u1ecb gi\u00e1c m\u00e0 kh\u00f4ng nhi\u1ec5m khu\u1ea9n \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e3 th\u1ea5t b\u1ea1i v\u1edbi ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb c\u0169 ho\u1eb7c b\u1ecb t\u00e1c d\u1ee5ng ph\u1ee5.<br \/>\n\u0110i\u1ec1u tr\u1ecb vi\u00eam m\u00e0ng b\u1ed3 \u0111\u00e0o Behcet k\u00e8m theo nh\u1eefng c\u01a1n vi\u00eam nh\u1eafc l\u1ea1i.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.0045%;\">H\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0<\/td>\n<td style=\"width: 74.1689%;\">Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em m\u1eafc th\u1eadn h\u01b0 ph\u1ee5 thu\u1ed9c steroid v\u00e0 kh\u00e1ng steroid \u1edf do c\u00e1c b\u1ec7nh \u1edf c\u1ea7u th\u1eadn.<br \/>\nD\u00f9ng v\u1edbi m\u1ee5c \u0111\u00edch l\u00e0m gi\u1ea3m b\u1ec7nh v\u00e0 duy tr\u00ec \u1ed5n \u0111\u1ecbnh b\u1ec7nh. C\u0169ng c\u00f3 th\u1ec3 d\u00f9ng \u0111\u1ec3 duy tr\u00ec s\u1ef1 thuy\u00ean gi\u1ea3m do \u0111i\u1ec1u tr\u1ecb b\u1eb1ng steroid, cho ph\u00e9p ng\u1eebng d\u00f9ng steroid.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.0045%;\">Vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p<\/td>\n<td style=\"width: 74.1689%;\">C\u00e1c tr\u01b0\u1eddng h\u1ee3p vi\u00eam nghi\u00eam tr\u1ecdng, \u0111ang ho\u1ea1t \u0111\u1ed9ng.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.0045%;\">B\u1ec7nh v\u1ea3y n\u1ebfn<\/td>\n<td style=\"width: 74.1689%;\">\u0110i\u1ec1u tr\u1ecb b\u1ec7nh v\u1ea3y n\u1ebfn nghi\u00eam tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n m\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.0045%;\">Vi\u00eam da c\u01a1 \u0111\u1ecba<\/td>\n<td style=\"width: 74.1689%;\">C\u1ea7n \u0111\u1ebfn \u0111i\u1ec1u tr\u1ecb to\u00e0n th\u00e2n \u0111\u1ed1i v\u1edbi vi\u00eam da c\u01a1 \u0111\u1ecba nghi\u00eam tr\u1ecdng.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c CKDCIPOL-N 100mg<\/h2>\n<p>Khi u\u1ed1ng c\u1ea7n nu\u1ed1t c\u1ea3 nang thu\u1ed1c. N\u00ean u\u1ed1ng c\u00f9ng v\u1edbi b\u1eefa \u0103n v\u00e0 tr\u00e1nh d\u00f9ng c\u00f9ng v\u1edbi n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi.<\/p>\n<p>C\u0103n c\u1ee9 v\u00e0o n\u1ed3ng \u0111\u1ed9 cyclosporin trong m\u00e1u ho\u1eb7c huy\u1ebft t\u01b0\u01a1ng \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh li\u1ec1u. Trong ng\u00e0y, n\u00ean u\u1ed1ng theo m\u1ed9t th\u1eddi gian bi\u1ec3u \u1ed5n \u0111\u1ecbnh.<\/p>\n<p>Gh\u00e9p t\u1ea1ng<\/p>\n<p>Gh\u00e9p t\u1ea1ng \u0111\u1eb7c<\/p>\n<ul>\n<li>Li\u1ec1u 10-15 mg\/kg trong v\u00f2ng 12 gi\u1edd tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt, chia 2 l\u1ea7n. Sau \u0111\u00f3, duy tr\u00ec h\u00e0ng ng\u00e0y trong 1-2 tu\u1ea7n sau ph\u1eabu thu\u1eadt. Gi\u1ea3m li\u1ec1u d\u1ea7n d\u1ea7n theo \u0111\u00fang v\u1edbi n\u1ed3ng \u0111\u1ed9 c\u1ee7a thu\u1ed1c trong m\u00e1u cho t\u1edbi khi li\u1ebfu duy tr\u00ec \u0111\u1ea1t kho\u1ea3ng 2-6 mg\/kg, chia 2 l\u1ea7n d\u00f9ng trong ng\u00e0y.<\/li>\n<li>C\u00f3 th\u1ec3 d\u00f9ng li\u1ec1u th\u1ea5p h\u01a1n n\u1ebfu d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch kh\u00e1c (v\u00ed d\u1ee5 kh\u1edfi \u0111\u1ea7u 3-6 mg\/kg, chia 2 l\u1ea7n).<\/li>\n<li>C\u00f3 th\u1ec3 truy\u1ec1n t\u0129nh m\u1ea1ch \u1edf ng\u01b0\u1eddi kh\u00f4ng dung n\u1ea1p cyclosporine u\u1ed1ng v\u1edbi li\u1ec1u b\u1eb1ng kho\u1ea3ng 1\/3 li\u1ec1u u\u1ed1ng, trong 2-6 gi\u1edd ho\u1eb7c l\u00e2u h\u01a1n. Khi ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 dung n\u1ea1p thu\u1ed1c u\u1ed1ng, ph\u1ea3i ng\u1eebng truy\u1ec1n t\u0129nh m\u1ea1ch ngay v\u00e0 chuy\u1ec3n sang d\u00f9ng d\u1ea1ng u\u1ed1ng c\u00e0ng s\u1edbm c\u00e0ng t\u1ed1t.<\/li>\n<\/ul>\n<p>Gh\u00e9p t\u1ee7y x\u01b0\u01a1ng<\/p>\n<p>T\u1eeb ng\u00e0y tr\u01b0\u1edbc khi gh\u00e9p cho t\u1edbi 2 tu\u1ea7n sau ph\u1eabu thu\u1eadt, u\u1ed1ng 12,5 -15 mg\/kg m\u1ed7i ng\u00e0y. Trong 3-6 th\u00e1ng sau \u0111\u00f3, u\u1ed1ng 12,5 mg\/kg m\u1ed7i ng\u00e0y r\u1ed3i gi\u1ea3m d\u1ea7n li\u1ec1u u\u1ed1ng (c\u00f3 th\u1ec3 d\u00f9ng cho t\u1edbi 1 n\u0103m sau khi gh\u00e9p).<\/p>\n<p>C\u00e1c tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng gh\u00e9p t\u1ea1ng<\/p>\n<p>Vi\u00eam m\u00e0ng b\u1ed3 \u0111\u00e0o n\u1ed9i sinh<\/p>\n<ul>\n<li>U\u1ed1ng m\u1ed7i ng\u00e0y 5 mg\/kg, chia 2 l\u1ea7n cho t\u1edbi khi gi\u1ea3m vi\u00eam, m\u00e0ng b\u1ed3 \u0111\u00e0o ho\u1ea1t \u0111\u1ed9ng v\u00e0 c\u1ea3i thi\u1ec7n th\u1ecb l\u1ef1c. Trong tr\u01b0\u1eddng h\u1ee3p n\u1ebfu kh\u00e1ng l\u1ea1i, c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean 7 mg\/kg\/ng\u00e0y trong th\u1eddi gian nh\u1ea5t \u0111\u1ecbnh.<\/li>\n<li>Ch\u1ec9 d\u00f9ng ri\u00eang CKDCIPOL-N ch\u01b0a ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c \u0111\u1ea7y \u0111\u1ee7 t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u00ec v\u1eady c\u00f3 th\u1ec3 d\u00f9ng th\u00eam corticoid to\u00e0n th\u00e2n v\u1edbi li\u1ec1u 0,2-0,6 mg\/kg prednisone h\u00e0ng ng\u00e0y ho\u1eb7c t\u01b0\u01a1ng \u0111\u01b0\u01a1ng.<\/li>\n<li>C\u1ea7n gi\u1ea3m li\u1ec1u d\u1ea7n d\u1ea7n cho t\u1edbi li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb duy tr\u00ec (kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 5 mg\/kg\/ng\u00e0y) trong th\u1eddi k\u1ef3 lui b\u1ec7nh.<\/li>\n<\/ul>\n<p>H\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0<\/p>\n<ul>\n<li>\u0110\u1ec3 l\u00e0m gi\u1ea3m b\u1ec7nh, li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 5 mg\/kg (v\u1edbi ng\u01b0\u1eddi l\u1edbn) v\u00e0 6 mg\/kg (v\u1edbi tr\u1ebb em) m\u1ed7i ng\u00e0y, chia 2 l\u1ea7n u\u1ed1ng, khi ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng, tr\u1eeb khi c\u00f3 protein-ni\u1ec7u. N\u1ebfu suy ch\u1ee9c n\u0103ng th\u1eadn, li\u1ec1u kh\u1edfi \u0111\u1ea7u m\u1ed7i ng\u00e0y kh\u00f4ng n\u00ean l\u1edbn h\u01a1n 2,5 mg\/kg\/ng\u00e0y.<\/li>\n<li>N\u00ean ph\u1ed1i h\u1ee3p v\u1edbi corticoid \u0111\u01b0\u1eddng u\u1ed1ng \u0111\u1ec3 c\u00f3 hi\u1ec7u qu\u1ea3 t\u1ed1t h\u01a1n.<\/li>\n<li>Ng\u1eebng d\u00f9ng thu\u1ed1c n\u1ebfu sau 3 th\u00e1ng \u0111i\u1ec1u tr\u1ecb m\u00e0 kh\u00f4ng c\u00f3 c\u1ea3i thi\u1ec7n.<\/li>\n<li>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u t\u00f9y t\u1eebng c\u00e1 th\u1ec3, kh\u00f4ng d\u00f9ng v\u01b0\u1ee3t qu\u00e1 5 mg\/kg\/ng\u00e0y (\u1edf ng\u01b0\u1eddi l\u1edbn) v\u00e0 6 mg\/kg\/ng\u00e0y (\u1edf tr\u1ebb em).<br \/>\nC\u1ea7n gi\u1ea3m li\u1ec1u d\u1ea7n d\u1ea7n cho t\u1edbi li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb duy tr\u00ec.<\/li>\n<\/ul>\n<p>Vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p<\/p>\n<ul>\n<li>Li\u1ec1u khuy\u1ebfn c\u00e1o m\u1ed7i ng\u00e0y l\u00e0 3 mg\/kg trong 6 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7u ti\u00ean, d\u00f9ng 2 l\u1ea7n\/ ng\u00e0y. C\u00f3 th\u1ec3 t\u0103ng d\u1ea7n li\u1ec1u khi \u0111\u1ed9 dung n\u1ea1p cho ph\u00e9p n\u1ebfu v\u1eabn ch\u01b0a \u0111\u1ee7 hi\u1ec7u l\u1ef1c, kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng qu\u00e1 5 mg\/kg m\u1ed7i ng\u00e0y. C\u00f3 th\u1ec3 c\u1ea7n k\u00e9o d\u00e0i \u0111i\u1ec1u tr\u1ecb t\u1edbi 12 tu\u1ea7n \u0111\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c hi\u1ec7u l\u1ef1c ho\u00e0n h\u1ea3o.<\/li>\n<li>Li\u1ec1u duy tr\u00ec c\u0103n c\u1ee9 v\u00e0o t\u1eebng c\u00e1 th\u1ec3 v\u00e0 \u0111\u1ed9 dung n\u1ea1p c\u1ee7a t\u1eebng ng\u01b0\u1eddi.<\/li>\n<li>C\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng v\u1edbi li\u1ec1u th\u1ea5p corticoid v\u00e0\/ho\u1eb7c thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid ho\u1eb7c li\u1ec1u th\u1ea5p methotrexat (d\u00f9ng t\u1eebng tu\u1ea7n l\u1ec5) \u1edf b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 \u0111\u00e1p \u1ee9ng \u0111\u1ea7y \u0111\u1ee7 n\u1ebfu ch\u1ec9 d\u00f9ng ri\u00eang methotrexat v\u00e0 d\u00f9ng tr\u01b0\u1edbc h\u1ebft 2,5 mg\/kg CKDCIPOL-N, chia 2 l\u1ea7n\/ng\u00e0y, t\u0103ng li\u1ec1u khi \u0111\u1ed9 dung n\u1ea1p cho ph\u00e9p.<\/li>\n<\/ul>\n<p>B\u1ec7nh v\u1ea3y n\u1ebfn<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb theo t\u1eebng c\u00e1 th\u1ec3.<\/p>\n<ul>\n<li>\u0110\u1ec3 gi\u00fap l\u00e0m thuy\u00ean gi\u1ea3m b\u1ec7nh, li\u1ec1u kh\u1edfi \u0111\u1ea7u khuy\u1ebfn c\u00e1o l\u00e0 2,5 mg\/kg\/ng\u00e0y, u\u1ed1ng 2 l\u1ea7n. C\u00f3 th\u1ec3 t\u0103ng d\u1ea7n li\u1ec1u h\u00e0ng ng\u00e0y, nh\u01b0ng kh\u00f4ng \u0111\u01b0\u1ee3c v\u01b0\u1ee3t qu\u00e1 5 mg\/kg n\u1ebfu sau 1 th\u00e1ng ch\u01b0a c\u00f3 c\u1ea3i thi\u1ec7n b\u1ec7nh. B\u1ec7nh nh\u00e2n m\u00e0 kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi c\u00e1c t\u1ed5n th\u01b0\u01a1ng v\u1ea3y n\u1ebfn trong 6 tu\u1ea7n d\u00f9ng 5 mg\/kg\/ng\u00e0y ho\u1eb7c v\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 li\u1ec1u hi\u1ec7u l\u1ef1c kh\u00f4ng t\u01b0\u01a1ng h\u1ee3p v\u1edbi c\u00e1c ch\u1ec9 d\u1eabn \u0111\u00e3 quy \u0111\u1ecbnh v\u1ec1 \u0111\u1ed9 an to\u00e0n th\u00ec c\u1ea7n ng\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>Kh\u1edfi \u0111\u1ea7u 5 mg\/kg\/ng\u00e0y \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 \u0111\u00fang v\u1edbi b\u1ec7nh nh\u00e2n m\u00e0 \u0111i\u1ec1u ki\u1ec7n \u0111\u00f2i h\u1ecfi c\u1ea3i thi\u1ec7n nhanh. C\u00f3 th\u1ec3 ng\u1eebng d\u00f9ng thu\u1ed1c khi \u0111\u00e3 \u0111\u1ea1t \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng mong mu\u1ed1n, n\u1ebfu t\u00e1i ph\u00e1t th\u00ec b\u1eaft \u0111\u1ea7u l\u1ea1i v\u1edbi li\u1ec1u c\u00f3 hi\u1ec7u l\u1ef1c tr\u01b0\u1edbc \u0111\u00f3. \u0110i\u1ec1u tr\u1ecb duy tr\u00ec ti\u1ebfp t\u1ee5c c\u00f3 th\u1ec3 c\u1ea7n thi\u1ebft v\u1edbi m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n.<\/li>\n<li>Li\u1ec1u \u0111i\u1ec1u tr\u1ecb duy tr\u00ec c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh theo c\u00e1 th\u1ec3 v\u1edbi m\u1ee9c li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u l\u1ef1c v\u00e0 kh\u00f4ng n\u00ean v\u01b0\u1ee3t qu\u00e1 5 mg\/kg\/ng\u00e0y.<\/li>\n<\/ul>\n<p>Vi\u00eam da c\u01a1 \u0111\u1ecba<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb theo t\u1eebng c\u00e1 th\u1ec3. Kho\u1ea3ng li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 2,5-5 mg\/kg\/ng\u00e0y, chia 2 l\u1ea7n.\u00a0 Li\u1ec1u h\u00e0ng ng\u00e0y n\u00ean t\u0103ng nhanh t\u1edbi t\u1ed1i \u0111a l\u00e0 5 mg\/kg n\u1ebfu li\u1ec1u kh\u1edfi \u0111\u1ea7u m\u1ed7i ng\u00e0y 2,5 mg\/kg kh\u00f4ng \u0111\u1ea1t \u0111\u00e1p \u1ee9ng mong mu\u1ed1n trong 2 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb. Trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p nghi\u00eam tr\u1ecdng, n\u1ebfu d\u00f9ng li\u1ec1u kh\u1edfi \u0111\u1ea7u m\u1ed7i ng\u00e0y l\u00e0 5 mg\/kg th\u00ec s\u1ef1 ki\u1ec3m so\u00e1t nhanh v\u00e0 \u0111\u1ea7y \u0111\u1ee7 c\u1ee7a b\u1ec7nh n\u00e0y s\u1ebd d\u1ec5 \u0111\u1ea1t h\u01a1n. Gi\u1ea3m d\u1ea7n li\u1ec1u khi \u0111\u00e3 \u0111\u1ea1t \u0111\u00e1p \u1ee9ng mong mu\u1ed1n v\u00e0 ng\u1eebng d\u00f9ng thu\u1ed1c n\u1ebfu c\u00f3 th\u1ec3. D\u00f9ng m\u1ed9t li\u1ec7u tr\u00ecnh ti\u1ebfp t\u1ee5c c\u1ee7a Cyclosporin \u0111\u1ec3 tr\u00e1nh t\u00e1i ph\u00e1t.<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c CKDCIPOL-N 100mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/p>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi Cyclosporin hay b\u1ea5t c\u1ee9 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Ng\u01b0\u1eddi b\u1ec7nh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p v\u00e0 b\u1ec7nh v\u1ea3y n\u1ebfn m\u00e0 ch\u1ee9c n\u0103ng th\u1eadn kh\u00f4ng b\u00ecnh th\u01b0\u1eddng.<\/li>\n<li>T\u0103ng huy\u1ebft \u00e1p kh\u00f4ng ki\u1ec3m so\u00e1t ho\u1eb7c c\u00e1c b\u1ec7nh \u00e1c t\u00ednh.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c CKDCIPOL-N 100mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Cyclosporin c\u1ea7n \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a th\u1ea7y thu\u1ed1c c\u00f3 kinh nghi\u1ec7m. Khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb ho\u1eb7c m\u1ed7i khi c\u00f3 thay \u0111\u1ed5i l\u1edbn trong li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb ph\u1ea3i \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n trong b\u1ec7nh vi\u1ec7n c\u00f3 trang b\u1ecb ph\u01b0\u01a1ng ti\u1ec7n x\u00e9t nghi\u1ec7m v\u00e0 h\u1ed3i s\u1ee9c \u0111\u1ea7y \u0111\u1ee7.<\/li>\n<li>Kh\u00f4ng n\u00ean d\u00f9ng Cyclosporin c\u00f9ng v\u1edbi nh\u1eefng thu\u1ed1c gi\u1ea3m mi\u1ec5n d\u1ecbch v\u00ec t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n v\u00e0 u lympho. Ch\u1ec9 truy\u1ec1n t\u0129nh m\u1ea1ch Cyclosporin cho ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng dung n\u1ea1p d\u1ea1ng thu\u1ed1c u\u1ed1ng \u0111\u1ec3 tr\u00e1nh ph\u1ea3n v\u1ec7 v\u00e0 theo d\u00f5i hi\u1ec7n t\u01b0\u1ee3ng d\u1ecb \u1ee9ng \u1edf ng\u01b0\u1eddi \u0111\u01b0\u1ee3c truy\u1ec1n. Khi truy\u1ec1n t\u0129nh m\u1ea1ch Cyclosporin, chu\u1ea9n b\u1ecb s\u1eb5n s\u00e0ng ph\u01b0\u01a1ng ti\u1ec7n tr\u1ee3 h\u00f4 h\u1ea5p, c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed3i s\u1ee9c v\u00e0 c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ph\u1ea3n v\u1ec7.<\/li>\n<li>Khi c\u1ea7n thi\u1ebft ph\u1ea3i \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u0111\u1ec3 tr\u00e1nh ng\u1ed9 \u0111\u1ed9c do n\u1ed3ng \u0111\u1ed9 thu\u1ed1c cao trong m\u00e1u ho\u1eb7c huy\u1ebft t\u01b0\u01a1ng, ho\u1eb7c d\u1ef1 ph\u00f2ng s\u1ef1 th\u1ea3i lo\u1ea1i m\u1ea3nh gh\u00e9p c\u00f3 th\u1ec3 x\u1ea3y ra do n\u1ed3ng \u0111\u1ed9 thu\u1ed1c th\u1ea5p. \u1ede nh\u1eefng ng\u01b0\u1eddi \u0111\u01b0\u1ee3c gh\u00e9p gan \u0111\u00f3ng lo\u1ea1i th\u00ec vi\u1ec7c theo d\u00f5i n\u1ed3ng \u0111\u1ed9 Cyclosporin trong m\u00e1u ho\u1eb7c huy\u1ebft t\u01b0\u01a1ng r\u1ea5t quan tr\u1ecdng, v\u00ec s\u1ef1 h\u1ea5p thu thu\u1ed1c \u1edf nh\u1eefng ng\u01b0\u1eddi n\u00e0y c\u00f3 th\u1ec3 th\u1ea5t th\u01b0\u1eddng.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>T\u00e1c d\u1ee5ng g\u00e2y \u0111\u1ed9c v\u1edbi th\u1eadn l\u00e0 ADR th\u01b0\u1eddng g\u1eb7p v\u00e0 quan tr\u1ecdng nh\u1ea5t v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng c\u1ee7a thu\u1ed1c.<\/p>\n<p>Ngo\u00e0i ra, c\u00f2n c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n sau:<\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 294px;\">\n<tbody>\n<tr style=\"height: 21px;\">\n<td style=\"width: 25.876%; height: 21px; text-align: center;\">T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/td>\n<td style=\"width: 74.124%; height: 21px; text-align: center;\">C\u01a1 quan v\u00e0 bi\u1ec3u hi\u1ec7n<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 25.876%; height: 21px;\" rowspan=\"6\">Th\u01b0\u1eddng g\u1eb7p<\/td>\n<td style=\"width: 74.124%; height: 21px;\">Tim m\u1ea1ch: T\u0103ng huy\u1ebft \u00e1p.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">Da: R\u1eadm l\u00f4ng, tr\u1ee9ng c\u00e1.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">Ti\u00eau h\u00f3a: Ph\u00ec \u0111\u1ea1i l\u1ee3i, kh\u00f3 ch\u1ecbu \u1edf b\u1ee5ng, bu\u1ed3n n\u00f4n, n\u00f4n.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">Th\u1ea7n kinh \u2013 c\u01a1 v\u00e0 x\u01b0\u01a1ng: Run, co c\u1ee9ng c\u01a1 ch\u00e2n.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">Th\u1eadn: \u0110\u1ed9c h\u1ea1i th\u1eadn.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">H\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng: Co gi\u1eadt, nh\u1ee9c \u0111\u1ea7u<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 25.876%; height: 21px;\" rowspan=\"6\">\u00cdt g\u1eb7p<\/td>\n<td style=\"width: 74.124%; height: 21px;\">Tim m\u1ea1ch: H\u1ea1 huy\u1ebft \u00e1p, nh\u1ecbp tim nhanh, c\u1ea3m gi\u00e1c \u1ea5m, \u0111\u1ecf b\u1eebng.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">N\u1ed9i ti\u1ebft v\u00e0 chuy\u1ec3n h\u00f3a: T\u0103ng kali huy\u1ebft, gi\u1ea3m magnesi huy\u1ebft, t\u0103ng acid uric huy\u1ebft.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">Ti\u00eau h\u00f3a: Vi\u00eam t\u1ee5y.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">Gan: \u0110\u1ed9c h\u1ea1i gan.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">Th\u1ea7n kinh \u2013 c\u01a1 v\u00e0 x\u01b0\u01a1ng: Vi\u00eam c\u01a1, d\u1ecb c\u1ea3m.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 74.124%; height: 21px;\">H\u00f4 h\u1ea5p: Suy h\u00f4 h\u1ea5p, vi\u00eam xoang.<\/td>\n<\/tr>\n<tr style=\"height: 21px;\">\n<td style=\"width: 100%; height: 21px;\" colspan=\"2\">Kh\u00e1c: T\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n, ph\u1ea3n v\u1ec7, v\u00e0 nh\u1ea1y c\u1ea3m v\u1edbi c\u00e1c m\u1ee9c c\u1ef1c \u0111\u1ed9 v\u1ec1 nhi\u1ec7t \u0111\u1ed9.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>N\u1ed3ng \u0111\u1ed9 Cyclosporin c\u00f3 th\u1ec3 thay \u0111\u1ed5i do thu\u1ed1c ho\u1eb7c th\u1ee9c \u0103n t\u00e1c d\u1ee5ng tr\u00ean cytochrom P450 3A (CYP 3A) \u1edf gan.<\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 48.1132%; text-align: center;\">Thu\u1ed1c t\u01b0\u01a1ng t\u00e1c v\u1edbi Cyclosporin<\/td>\n<td style=\"width: 51.8868%; text-align: center;\">T\u00e1c \u0111\u1ed9ng<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 48.1132%;\">Carbamaze\u00adpin, phenobarbital, phenytoin, rifampin, isoniazid<\/td>\n<td style=\"width: 51.8868%;\">L\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Cyclosporin.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 48.1132%;\">Azithromycin, clarithromycin, diltiazem, itraconazol erythromycin, fluconazol, ketoconazol, nicardipin, verapamil<\/td>\n<td style=\"width: 51.8868%;\">L\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Cyclosporin.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 48.1132%;\">Aminoglyco- sid, amphotericin B, acyclovir<\/td>\n<td style=\"width: 51.8868%;\">L\u00e0m t\u0103ng t\u00e1c d\u1ee5ng \u0111\u1ed9c h\u1ea1i th\u1eadn c\u1ee7a Cyclosporin.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 48.1132%;\">Lovasta\u00adtin<\/td>\n<td style=\"width: 51.8868%;\">D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi Cyclosporin c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n nh\u01b0: ti\u00eau h\u1ee7y c\u01a1 v\u00e2n, vi\u00eam c\u01a1, \u0111au c\u01a1, suy th\u1eadn c\u1ea5p.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 48.1132%;\">Nifedipin<\/td>\n<td style=\"width: 51.8868%;\">T\u0103ng nguy c\u01a1 s\u1ea3n l\u1ee3i khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi Cyclosporin.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 48.1132%;\">Thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch kh\u00e1c<\/td>\n<td style=\"width: 51.8868%;\">L\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n v\u00e0 u lympho.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<h4>Ph\u1ee5 n\u1eef c\u00f3 thai<\/h4>\n<p>Cyclosporin qua \u0111\u01b0\u1ee3c nhau thai. Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng Cyclosporin cho ph\u1ee5 n\u1eef mang thai v\u00ec v\u1eady ch\u1ec9 s\u1eed d\u1ee5ng Cyclosporin trong th\u1eddi k\u00ec mang thai khi c\u00e2n nh\u1eafc l\u1ee3i \u00edch nhi\u1ec1u h\u01a1n nguy c\u01a1.<\/p>\n<h4>Ph\u1ee5 n\u1eef cho con b\u00fa<\/h4>\n<p>Cyclosporin v\u00e0o \u0111\u01b0\u1ee3c trong s\u1eefa v\u00ec v\u1eady c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c h\u1ea1i b\u1ea5t l\u1ee3i \u0111\u1ed1i v\u1edbi tr\u1ebb. Khi ng\u01b0\u1eddi m\u1eb9 \u0111ang d\u00f9ng Cyclosporin c\u1ea7n tr\u00e1nh kh\u00f4ng cho con b\u00fa.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng<\/p>\n<p>Qu\u00e1 li\u1ec1u Cyclosporin c\u00f3 th\u1ec3 g\u00e2y nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng g\u1eb7p \u1edf m\u1ee9c \u0111\u1ed9 n\u1eb7ng h\u01a1n. \u0110\u1ed9c v\u1edbi gan v\u00e0 \u0111\u1ed9c v\u1edbi th\u1eadn c\u00f3 th\u1ec3 x\u1ea3y ra nh\u01b0ng c\u00f3 th\u1ec3 h\u1ebft sau khi thu\u1ed1c th\u1ea3i tr\u1eeb ho\u1eb7c ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb<\/p>\n<p>Khi qu\u00e1 li\u1ec1u u\u1ed1ng c\u1ea5p t\u00ednh c\u1ea7n g\u00e2y n\u00f4n \u0111\u1ec3 l\u00e0m s\u1ea1ch d\u1ea1 d\u00e0y. Cho \u0111\u1ebfn 2 gi\u1edd sau khi u\u1ed1ng bi\u1ec7n ph\u00e1p g\u00e2y n\u00f4n c\u00f3 th\u1ec3 c\u00f3 \u00edch.<br \/>\nC\u00f3 th\u1ec3 r\u1eeda d\u1ea1 d\u00e0y n\u1ebfu c\u00f3 s\u1eb5n ph\u01b0\u01a1ng ti\u1ec7n khi ng\u01b0\u1eddi b\u1ec7nh h\u00f4n m\u00ea, c\u00f3 c\u01a1n \u0111\u1ed9ng kinh ho\u1eb7c m\u1ea5t ph\u1ea3n x\u1ea1 h\u1ea7u \u0111\u1ec3 ph\u00f2ng tr\u00e1nh ng\u01b0\u1eddi b\u1ec7nh h\u00edt ph\u1ea3i ch\u1ea5t th\u1ea3i tr\u1eeb d\u1ea1 d\u00e0y. Ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, h\u1ed3i s\u1ee9c. Ng\u1eebng thu\u1ed1c trong v\u00e0i ng\u00e0y ho\u1eb7c b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi Cyclosporin c\u00e1ch ng\u00e0y cho t\u1edbi khi ng\u01b0\u1eddi b\u1ec7nh \u1ed5n \u0111\u1ecbnh khi x\u1ea3y ra qu\u00e1 li\u1ec1u Cyclosporin.<\/p>\n<h2>Thu\u1ed1c CKDCIPOL-N 100mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, <strong>gi\u00e1 thu\u1ed1c CKDCIPOL-N 100mg<\/strong> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline 0868 552 633 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/hmm88i.com\/drug\/thuoc-ckdmyrept-tab-500mg\/\">Ckdmyrept Tab. 500mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m Chong Kun Dang Pharmaceutical Corp \u2013 H\u00e0n Qu\u1ed1c ch\u1ee9a Mycophenolate mofetil 500mg c\u00f3 d\u1ea1ng b\u00e0o ch\u1ebf l\u00e0 vi\u00ean n\u00e9n bao phim. Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi Cyclosporine va Corticosteroid \u0111\u1ec3 d\u1ef1 ph\u00f2ng hi\u1ec7n t\u01b0\u1ee3ng th\u1ea3i gh\u00e9p c\u1ea5p t\u00ednh, th\u1ea3i gh\u00e9p l\u1ea7n \u0111\u1ea7u, \u0111\u00e1p \u1ee9ng k\u00e9m \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n gh\u00e9p gan kh\u00f4ng c\u00f9ng huy\u1ebft th\u1ed1ng, gh\u00e9p th\u1eadn, gh\u00e9p tim. Thu\u1ed1c c\u00f3 gi\u00e1 kho\u1ea3ng 4.900.000 \u0111\u1ed3ng\/ 1 h\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.<\/p>\n<p>Thu\u1ed1c <a href=\"https:\/\/hmm88i.com\/drug\/ckdcipol-n-25\/\">Ckdcipol N 25<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Suheung Capsule Co., Ltd \u2013 H\u00c0N QU\u1ed0C ch\u1ee9a Cyclosporin 25mg. Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi vi\u00ean nang m\u1ec1m v\u00e0 \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 600.000 \u0111\u1ed3ng\/ h\u1ed9p 10 v\u1ec9 x 5 vi\u00ean.<\/p>\n<h2>T\u1ea1i sao n\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c?<\/h2>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 63.0728%; text-align: center;\">\u01afu \u0111i\u1ec3m<\/td>\n<td style=\"width: 36.9272%; text-align: center;\">Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 63.0728%;\">Cyclosporin l\u00e0 m\u1ed9t thu\u00f4c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch m\u1ea1nh hay \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ng\u0103n ch\u1eb7n s\u1ef1 \u0111\u00e0o th\u1ea3i c\u1ee7a c\u00e1c c\u01a1 quan c\u1ea5y gh\u00e9p v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh c\u00f3 ngu\u1ed3n g\u1ed1c t\u1ef1 mi\u1ec5n d\u1ecbch.<\/td>\n<td style=\"width: 36.9272%;\">T\u00e1c d\u1ee5ng ph\u1ee5 hay g\u1eb7p nh\u1ea5t c\u1ee7a thu\u1ed1c l\u00e0 g\u00e2y \u0111\u1ed9c v\u1edbi th\u1eadn.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 63.0728%;\">Cyclosporin \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch m\u1ea1nh nh\u01b0ng h\u1ea7u nh\u01b0 kh\u00f4ng g\u00e2y \u0111\u1ed9c cho t\u1ee7y.<\/td>\n<td style=\"width: 36.9272%;\"><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 63.0728%;\">CKDCIPOL-N 100mg ch\u1ee9a Cyclosporin \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi nh\u0169 t\u01b0\u01a1ng c\u00f3 \u01b0u \u0111i\u1ec3m l\u00e0: sinh kh\u1ea3 d\u1ee5ng l\u1edbn h\u01a1n d\u1ea1ng u\u1ed1ng v\u00e0 th\u1ee9c \u0103n ch\u1ee9a nhi\u1ec1u ch\u1ea5t b\u00e9o kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ea5p thu thu\u1ed1c.<\/td>\n<td style=\"width: 36.9272%;\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u00e1c gi\u1ea3 Richard J. Ptachcinski v\u00e0 c\u1ed9ng s\u1ef1 (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 04 th\u00e1ng 11 n\u0103m 2012). <em>Clinical pharmacokinetics of cyclosporin<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 11 th\u00e1ng 09 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/link.springer.com\/article\/10.2165\/00003088-198611020-00002\" rel=\"noopener\">https:\/\/link.springer.com\/article\/10.2165\/00003088-198611020-00002<\/a><\/li>\n<li>T\u00e1c gi\u1ea3\u00a0 Can Med PGS J. (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 01 th\u00e1ng 05 n\u0103m 1982). <em>Cyclosporin A: a powerful immunosuppressant<\/em>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 11 th\u00e1ng 09 n\u0103m 2023, t\u1eeb <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1863293\/\" rel=\"noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1863293\/<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c CKDCIPOL-N 100mg \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong gh\u00e9p c\u00e1c m\u00f4 v\u00e0 c\u01a1 quan v\u1edbi m\u1ee5c \u0111\u00edch d\u1ef1 ph\u00f2ng b\u1ec7nh do m\u1ea3nh gh\u00e9p g\u00e2y ra cho ng\u01b0\u1eddi nh\u1eadn v\u00e0 d\u1ef1 ph\u00f2ng lo\u1ea1i b\u1ecf m\u1ea3nh gh\u00e9p sau khi gh\u00e9p c\u00e1c m\u00f4 c\u01a1 quan nh\u01b0: t\u1ee7y x\u01b0\u01a1ng, th\u1eadn, gan, t\u1ee5y, tim v\u00e0 tim \u2013 ph\u1ed5i.<\/p>\n","protected":false},"author":1,"featured_media":41678,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-41677","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product\/41677","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/comments?post=41677"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/media\/41678"}],"wp:attachment":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/media?parent=41677"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product_cat?post=41677"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product_tag?post=41677"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}