{"id":142067,"date":"2025-09-28T19:17:46","date_gmt":"2025-09-28T12:17:46","guid":{"rendered":"https:\/\/hmm88i.com\/drug\/?post_type=product&p=142067"},"modified":"2025-09-28T19:18:57","modified_gmt":"2025-09-28T12:18:57","slug":"opesinkast-5","status":"publish","type":"product","link":"https:\/\/hmm88i.com\/drug\/opesinkast-5\/","title":{"rendered":"Opesinkast 5"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> Opesinkast 5<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m OPV, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110089924 (VD-24247-16).<\/strong><\/p>\n

Opesinkast 5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n

M\u1ed7i vi\u00ean n\u00e9n ph\u00e2n t\u00e1n trong mi\u1ec7ng Opesinkast 5 <\/strong>ch\u1ee9a:<\/p>\n\n\n\n\n
Ho\u1ea1t ch\u1ea5t<\/td>\nMontelukast 5mg<\/strong> (d\u01b0\u1edbi d\u1ea1ng Montelukast sodium)<\/td>\n<\/tr>\n
T\u00e1 d\u01b0\u1ee3c<\/td>\nManitol 60, natri croscarmellose, aspartam, b\u1ed9t m\u00f9i tr\u00e1i c\u00e2y t\u1ed5ng h\u1ee3p, oxyd s\u1eaft \u0111\u1ecf, magnesi stearat<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Tr\u00ecnh b\u00e0y<\/h3>\n

S\u0110K: 893110089924 (VD-24247-16)<\/p>\n

D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n ph\u00e2n t\u00e1n trong mi\u1ec7ng<\/p>\n

Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean; H\u1ed9p 5 v\u1ec9 x 10 vi\u00ean; H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n

Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n

\"Opesinkast
Opesinkast 5 d\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb hen, ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh<\/figcaption><\/figure>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Opesinkast 5<\/h2>\n

C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n

Trong b\u1ec7nh hen v\u00e0 vi\u00eam m\u0169i d\u1ecb \u1ee9ng, c\u01a1 th\u1ec3 ti\u1ebft ra m\u1ed9t ch\u1ea5t g\u00e2y vi\u00eam m\u1ea1nh l\u00e0 leukotriene D4 (LTD4). Ch\u1ea5t n\u00e0y g\u00e2y co th\u1eaft ph\u1ebf qu\u1ea3n, t\u0103ng ti\u1ebft d\u1ecbch nh\u1ea7y v\u00e0 ph\u00f9 n\u1ec1 \u0111\u01b0\u1eddng th\u1edf, d\u1eabn \u0111\u1ebfn c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 kh\u00f3 th\u1edf, ngh\u1eb9t m\u0169i.<\/p>\n

Montelukast ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n LTD4 g\u1eafn v\u00e0o \u0111i\u1ec3m ti\u1ebfp nh\u1eadn (receptor) c\u1ee7a n\u00f3 tr\u00ean t\u1ebf b\u00e0o. B\u1eb1ng vi\u1ec7c “kh\u00f3a” l\u1ea1i \u0111i\u1ec3m ti\u1ebfp nh\u1eadn n\u00e0y, Montelukast \u0111\u00e3 v\u00f4 hi\u1ec7u h\u00f3a t\u00e1c \u0111\u1ed9ng c\u1ee7a LTD4, t\u1eeb \u0111\u00f3 gi\u00fap gi\u1ea3m vi\u00eam, l\u00e0m \u0111\u01b0\u1eddng th\u1edf gi\u00e3n ra v\u00e0 c\u1ea3i thi\u1ec7n hi\u1ec7u qu\u1ea3 c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh.<\/p>\n

\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n

H\u1ea5p thu: Montelukast \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh sau khi u\u1ed1ng, v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 2 \u0111\u1ebfn 4 gi\u1edd.<\/p>\n

Ph\u00e2n b\u1ed1: H\u01a1n 99% Montelukast li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, gi\u00fap thu\u1ed1c l\u01b0u h\u00e0nh trong m\u00e1u v\u00e0 \u0111i \u0111\u1ebfn c\u00e1c m\u00f4 \u0111\u00edch.<\/p>\n

Chuy\u1ec3n h\u00f3a: Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu t\u1ea1i gan b\u1edfi c\u00e1c enzyme cytochrom P450, c\u1ee5 th\u1ec3 l\u00e0 CYP3A4, CYP2C8 v\u00e0 CYP2C9.<\/p>\n

Th\u1ea3i tr\u1eeb: Montelukast v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a n\u00f3 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng m\u1eadt v\u00e0 ra ngo\u00e0i theo ph\u00e2n.<\/p>\n

Thu\u1ed1c Opesinkast 5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n

D\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh: D\u00e0nh cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em, \u0111\u1eb7c bi\u1ec7t \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n hen nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh kh\u00f4ng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t t\u1ed1t b\u1eb1ng c\u00e1c li\u1ec7u ph\u00e1p kh\u00e1c.<\/p>\n

L\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a vi\u00eam m\u0169i d\u1ecb \u1ee9ng: Bao g\u1ed3m c\u1ea3 vi\u00eam m\u0169i d\u1ecb \u1ee9ng theo m\u00f9a v\u00e0 vi\u00eam m\u0169i d\u1ecb \u1ee9ng quanh n\u0103m.<\/p>\n

D\u1ef1 ph\u00f2ng co th\u1eaft ph\u1ebf qu\u1ea3n do g\u1eafng s\u1ee9c: Gi\u00fap ng\u0103n ng\u1eeba c\u01a1n kh\u00f3 th\u1edf kh\u1edfi ph\u00e1t sau c\u00e1c ho\u1ea1t \u0111\u1ed9ng th\u1ec3 ch\u1ea5t.<\/p>\n

Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c<\/h2>\n

Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c<\/h3>\n

Li\u1ec1u d\u00f9ng ph\u1ea3i tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t theo ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129. Li\u1ec1u khuy\u1ebfn c\u00e1o th\u00f4ng th\u01b0\u1eddng cho tr\u1ebb t\u1eeb 6-14 tu\u1ed5i trong \u0111i\u1ec1u tr\u1ecb hen ph\u1ebf qu\u1ea3n ho\u1eb7c vi\u00eam m\u0169i d\u1ecb \u1ee9ng l\u00e0 1 vi\u00ean Opesinkast 5 mg\/l\u1ea7n\/ng\u00e0y, u\u1ed1ng v\u00e0o bu\u1ed5i t\u1ed1i.<\/p>\n

C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c<\/h3>\n

L\u01b0u \u00fd quan tr\u1ecdng: \u0110\u00e2y l\u00e0 thu\u1ed1c d\u00f9ng \u0111\u1ec3 d\u1ef1 ph\u00f2ng v\u00e0 ki\u1ec3m so\u00e1t b\u1ec7nh m\u1ea1n t\u00ednh.
\nTuy\u1ec7t \u0111\u1ed1i kh\u00f4ng d\u00f9ng \u0111\u1ec3 c\u1eaft c\u01a1n hen c\u1ea5p ho\u1eb7c \u0111i\u1ec1u tr\u1ecb \u0111\u1ee3t kh\u00f3 th\u1edf c\u1ea5p t\u00ednh. B\u1ec7nh nh\u00e2n ph\u1ea3i lu\u00f4n c\u00f3 s\u1eb5n thu\u1ed1c c\u1eaft c\u01a1n t\u00e1c d\u1ee5ng nhanh (nh\u01b0 Salbutamol) theo ch\u1ec9 d\u1eabn c\u1ee7a b\u00e1c s\u0129.<\/p>\n

\u0110\u1eb7t vi\u00ean thu\u1ed1c tr\u1ef1c ti\u1ebfp l\u00ean l\u01b0\u1ee1i, thu\u1ed1c s\u1ebd t\u1ef1 tan nhanh trong v\u00e0i gi\u00e2y v\u00e0 c\u00f3 th\u1ec3 nu\u1ed1t c\u00f9ng v\u1edbi n\u01b0\u1edbc b\u1ecdt.<\/p>\n

C\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng v\u1edbi n\u01b0\u1edbc ho\u1eb7c kh\u00f4ng, thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/p>\n

Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Opesinkast 5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n

Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh tuy\u1ec7t \u0111\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn c\u1ea3m hay d\u1ecb \u1ee9ng v\u1edbi Montelukast ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n

Th\u1eadn tr\u1ecdng<\/h3>\n

Nguy c\u01a1 v\u1ec1 c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n tr\u00ean th\u1ea7n kinh-t\u00e2m th\u1ea7n (Neuropsychiatric events): B\u1ec7nh nh\u00e2n v\u00e0 ng\u01b0\u1eddi nh\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ef9 l\u01b0\u1ee1ng v\u1ec1 c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u00f3 th\u1ec3 x\u1ea3y ra, bao g\u1ed3m:<\/p>\n