{"id":123476,"date":"2025-06-14T16:41:49","date_gmt":"2025-06-14T09:41:49","guid":{"rendered":"https:\/\/hmm88i.com\/drug\/?post_type=product&#038;p=123476"},"modified":"2025-07-24T11:48:19","modified_gmt":"2025-07-24T04:48:19","slug":"savi-gemfibrozil-600","status":"publish","type":"product","link":"https:\/\/hmm88i.com\/drug\/savi-gemfibrozil-600\/","title":{"rendered":"Savi Gemfibrozil 600"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/hmm88i.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Savi Gemfibrozil 600 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Savi, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110293923 (VD-28033-17).<\/strong><\/p>\n<h2>Savi Gemfibrozil 600 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean n\u00e9n bao phim <strong>Savi Gemfibrozil 600<\/strong> ch\u1ee9a 600mg<strong> Gemfibrozil<\/strong> c\u00f9ng v\u1edbi c\u00e1c t\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110293923 (VD-28033-17)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_123482\" aria-describedby=\"caption-attachment-123482\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-123482\" src=\"https:\/\/hmm88i.com\/drug\/wp-content\/uploads\/2025\/06\/Savi-Gemfibrozil-600.jpg\" alt=\"Savi Gemfibrozil 600 \u0111i\u1ec1u tr\u1ecb t\u0103ng lipid m\u00e1u th\u1ec3 h\u1ed7n h\u1ee3p\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/hmm88i.com\/drug\/wp-content\/uploads\/2025\/06\/Savi-Gemfibrozil-600.jpg 1200w, https:\/\/hmm88i.com\/drug\/wp-content\/uploads\/2025\/06\/Savi-Gemfibrozil-600-600x400.jpg 600w, https:\/\/hmm88i.com\/drug\/wp-content\/uploads\/2025\/06\/Savi-Gemfibrozil-600-768x512.jpg 768w, https:\/\/hmm88i.com\/drug\/wp-content\/uploads\/2025\/06\/Savi-Gemfibrozil-600-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-123482\" class=\"wp-caption-text\">Savi Gemfibrozil 600 \u0111i\u1ec1u tr\u1ecb t\u0103ng lipid m\u00e1u th\u1ec3 h\u1ed7n h\u1ee3p<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Savi Gemfibrozil 600<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Gemfibrozil ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch k\u00edch th\u00edch ho\u1ea1t \u0111\u1ed9ng c\u1ee7a receptor PPAR-\u03b1 (Peroxisome Proliferator-Activated Receptor Alpha) trong t\u1ebf b\u00e0o gan v\u00e0 m\u00f4 m\u1ee1. \u0110i\u1ec1u n\u00e0y d\u1eabn \u0111\u1ebfn:<\/p>\n<ul>\n<li>T\u0103ng c\u01b0\u1eddng qu\u00e1 tr\u00ecnh oxy h\u00f3a axit b\u00e9o: Gi\u00fap c\u01a1 th\u1ec3 s\u1eed d\u1ee5ng ch\u1ea5t b\u00e9o hi\u1ec7u qu\u1ea3 h\u01a1n.<\/li>\n<li>Gi\u1ea3m t\u1ed5ng h\u1ee3p triglyceride v\u00e0 cholesterol t\u1ea1i gan: L\u00e0m gi\u1ea3m s\u1ea3n xu\u1ea5t c\u00e1c lo\u1ea1i m\u1ee1 x\u1ea5u.<\/li>\n<li>Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 VLDL (lipoprotein t\u1ef7 tr\u1ecdng r\u1ea5t th\u1ea5p): VLDL l\u00e0 m\u1ed9t lo\u1ea1i lipoprotein gi\u00e0u triglyceride, c\u00f3 h\u1ea1i cho tim m\u1ea1ch. Gemfibrozil l\u00e0m t\u0103ng ho\u1ea1t t\u00ednh c\u1ee7a lipoprotein lipase, th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh th\u1ee7y ph\u00e2n triglyceride trong VLDL.<\/li>\n<li>T\u0103ng nh\u1eb9 n\u1ed3ng \u0111\u1ed9 HDL (lipoprotein t\u1ef7 tr\u1ecdng cao): HDL l\u00e0 cholesterol t\u1ed1t, gi\u00fap v\u1eadn chuy\u1ec3n cholesterol d\u01b0 th\u1eeba v\u1ec1 gan \u0111\u1ec3 th\u1ea3i tr\u1eeb.<\/li>\n<li>Gi\u1ea3m k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u: G\u00f3p ph\u1ea7n gi\u1ea3m nguy c\u01a1 m\u1eafc c\u00e1c b\u1ec7nh l\u00fd tim m\u1ea1ch.<\/li>\n<\/ul>\n<p>\u0110\u1eb7c bi\u1ec7t, gemfibrozil c\u00f2n thay \u0111\u1ed5i th\u00e0nh ph\u1ea7n c\u1ee7a VLDL b\u1eb1ng c\u00e1ch gi\u1ea3m s\u1ea3n xu\u1ea5t apoC-III \u1edf gan, m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf ho\u1ea1t t\u00ednh c\u1ee7a lipoprotein lipase.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Gemfibrozil \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng v\u00e0 g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n (sinh kh\u1ea3 d\u1ee5ng 98 \u00b1 1%) khi u\u1ed1ng tr\u01b0\u1edbc b\u1eefa \u0103n, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 1-2 gi\u1edd.<\/li>\n<li>Ph\u00e2n b\u1ed1: H\u01a1n 97% gemfibrozil g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng v\u00e0 ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i trong c\u01a1 th\u1ec3, v\u1edbi n\u1ed3ng \u0111\u1ed9 cao h\u01a1n \u1edf gan, th\u1eadn v\u00e0 ru\u1ed9t.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Thu\u1ed1c ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c oxy h\u00f3a th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a d\u1ea1ng hydroxymethyl v\u00e0 carboxyl, sau \u0111\u00f3 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u (70% li\u1ec1u u\u1ed1ng) d\u01b0\u1edbi d\u1ea1ng li\u00ean h\u1ee3p v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a.<\/li>\n<li>T\u01b0\u01a1ng t\u00e1c chuy\u1ec3n h\u00f3a: Gemfibrozil c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf m\u1ea1nh c\u00e1c enzyme CYP2C8, CYP2C9, CYP2C19, CYP1A2, c\u00f9ng v\u1edbi c\u00e1c ch\u1ea5t v\u1eadn chuy\u1ec3n nh\u01b0 UGTA1, UGTA3 v\u00e0 OATP1B1.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Savi Gemfibrozil 600 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Savi Gemfibrozil 600 l\u00e0 m\u1ed9t li\u1ec7u ph\u00e1p b\u1ed5 tr\u1ee3 cho ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng v\u00e0 t\u1eadp luy\u1ec7n, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p r\u1ed1i lo\u1ea1n lipid m\u00e1u v\u00e0 d\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 tim m\u1ea1ch c\u1ee5 th\u1ec3:<\/p>\n<ul>\n<li>T\u0103ng Triglyceride Huy\u1ebft Thanh Nghi\u00eam Tr\u1ecdng: \u00c1p d\u1ee5ng cho b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 triglyceride trong m\u00e1u cao \u0111\u00e1ng k\u1ec3, c\u00f3 ho\u1eb7c kh\u00f4ng k\u00e8m theo gi\u1ea3m n\u1ed3ng \u0111\u1ed9 cholesterol HDL (lipoprotein t\u1ef7 tr\u1ecdng cao).<\/li>\n<li>R\u1ed1i Lo\u1ea1n Lipid M\u00e1u H\u1ed7n H\u1ee3p: S\u1eed d\u1ee5ng khi b\u1ec7nh nh\u00e2n kh\u00f4ng dung n\u1ea1p ho\u1eb7c c\u00f3 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p statin.<\/li>\n<li>T\u0103ng Cholesterol M\u00e1u Nguy\u00ean Ph\u00e1t: Ch\u1ec9 \u0111\u1ecbnh trong tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ec3 s\u1eed d\u1ee5ng ho\u1eb7c c\u00f3 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p statin.<\/li>\n<li>Gi\u1ea3m T\u1ef7 L\u1ec7 M\u1eafc B\u1ec7nh Tim M\u1ea1ch: \u0110\u01b0\u1ee3c xem x\u00e9t \u1edf nam gi\u1edbi c\u00f3 n\u1ed3ng \u0111\u1ed9 non-HDL cholesterol cao v\u00e0 nguy c\u01a1 cao m\u1eafc c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch, \u0111\u1eb7c bi\u1ec7t khi kh\u00f4ng th\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng statin.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Savi Gemfibrozil 600<\/h2>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn: Li\u1ec1u khuy\u1ebfn c\u00e1o dao \u0111\u1ed9ng t\u1eeb 900 mg \u0111\u1ebfn 1200 mg m\u1ed7i ng\u00e0y.\n<ul>\n<li>Li\u1ec1u 1200 mg\/ng\u00e0y c\u00f3 th\u1ec3 chia th\u00e0nh 2 l\u1ea7n u\u1ed1ng (600 mg x 2 l\u1ea7n\/ng\u00e0y) ho\u1eb7c d\u00f9ng m\u1ed9t li\u1ec1u duy nh\u1ea5t.<\/li>\n<li>Li\u1ec1u 900 mg\/ng\u00e0y c\u00f3 th\u1ec3 d\u00f9ng m\u1ed9t l\u1ea7n duy nh\u1ea5t, 30 ph\u00fat tr\u01b0\u1edbc b\u1eefa \u0103n t\u1ed1i.<\/li>\n<\/ul>\n<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i (tr\u00ean 65 tu\u1ed5i): Li\u1ec1u d\u00f9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 ng\u01b0\u1eddi l\u1edbn.<\/li>\n<li>Tr\u1ebb em: Hi\u1ec7n t\u1ea1i kh\u00f4ng c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u l\u00e2m s\u00e0ng \u0111\u1ec3 khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng Gemfibrozil cho tr\u1ebb em.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn:\n<ul>\n<li>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy th\u1eadn nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh, li\u1ec1u kh\u1edfi \u0111\u1ea7u khuy\u1ebfn c\u00e1o l\u00e0 900 mg\/ng\u00e0y. C\u1ea7n th\u1eadn tr\u1ecdng v\u00e0 \u0111\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng th\u1eadn tr\u01b0\u1edbc khi c\u00e2n nh\u1eafc t\u0103ng li\u1ec1u.<\/li>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng Gemfibrozil cho b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng (m\u1ee9c l\u1ecdc c\u1ea7u th\u1eadn \u01b0\u1edbc t\u00ednh \u226430 mL\/phu\u02cat\/1.73m2).<\/li>\n<\/ul>\n<\/li>\n<li>B\u1ec7nh nh\u00e2n suy gan: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng Gemfibrozil cho b\u1ec7nh nh\u00e2n suy gan.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Savi Gemfibrozil 600<\/h2>\n<p>N\u00ean u\u1ed1ng 30 ph\u00fat tr\u01b0\u1edbc b\u1eefa \u0103n s\u00e1ng ho\u1eb7c t\u1ed1i. Kh\u00f4ng nhai, ng\u1eadm hay nghi\u1ec1n vi\u00ean thu\u1ed1c.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Savi Gemfibrozil 600 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi Gemfibrozil ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c Savi Gemfibrozil 600.<\/li>\n<li>Suy gan, suy th\u1eadn n\u1eb7ng.<\/li>\n<li>B\u1ec7nh t\u00fai m\u1eadt, b\u1ec7nh \u0111\u01b0\u1eddng m\u1eadt (c\u00f3 ti\u1ec1n s\u1eed ho\u1eb7c \u0111ang m\u1eafc).<\/li>\n<li>\u0110ang d\u00f9ng \u0111\u1ed3ng th\u1eddi Repaglinid, Dasabuvir ho\u1eb7c Simvastatin.<\/li>\n<li>Khi d\u00f9ng fibrat c\u00f3 ph\u1ea3n \u1ee9ng \u0111\u1ed9c t\u00ednh v\u1edbi \u00e1nh s\u00e1ng.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Savi Gemfibrozil 600<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>R\u1ed1i lo\u1ea1n c\u01a1 (b\u1ec7nh c\u01a1, ti\u00eau c\u01a1 v\u00e2n): Gemfibrozil c\u00f3 th\u1ec3 g\u00e2y vi\u00eam c\u01a1, b\u1ec7nh c\u01a1 v\u00e0 t\u0103ng CPK. C\u1ea7n ng\u01b0ng thu\u1ed1c n\u1ebfu xu\u1ea5t hi\u1ec7n \u0111au c\u01a1 lan t\u1ecfa ho\u1eb7c CPK &gt; 5 l\u1ea7n gi\u1edbi h\u1ea1n b\u00ecnh th\u01b0\u1eddng.<\/li>\n<li>Ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf HMG-CoA reductase (Statin): T\u0103ng nguy c\u01a1 vi\u00eam c\u01a1 nghi\u00eam tr\u1ecdng v\u00e0 ti\u00eau c\u01a1 v\u00e2n. Ch\u1ec9 ph\u1ed1i h\u1ee3p khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 v\u00e0 c\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 CPK.<\/li>\n<li>Ng\u01b0\u1eddi b\u1ecb s\u1ecfi m\u1eadt: Gemfibrozil l\u00e0m t\u0103ng b\u00e0i ti\u1ebft cholesterol v\u00e0o m\u1eadt, t\u0103ng nguy c\u01a1 h\u00ecnh th\u00e0nh s\u1ecfi m\u1eadt. Ng\u01b0ng thu\u1ed1c n\u1ebfu ph\u00e1t hi\u1ec7n s\u1ecfi.<\/li>\n<li>Theo d\u00f5i \u0111\u1ecbnh k\u1ef3: C\u1ea7n ki\u1ec3m tra \u0111\u1ecbnh k\u1ef3 lipid huy\u1ebft thanh, ch\u1ee9c n\u0103ng gan v\u00e0 s\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o m\u00e1u trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb. Ng\u1eebng thu\u1ed1c n\u1ebfu c\u00f3 b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng gan.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>R\u1ea5t th\u01b0\u1eddng g\u1eb7p (\u2265 1\/10): Kh\u00f3 ti\u00eau.<\/li>\n<li>Th\u01b0\u1eddng g\u1eb7p (1\/100 \u2264 ADR &lt; 1\/10): Ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, \u0111\u1ea7y h\u01a1i, t\u00e1o b\u00f3n, ph\u00e1t ban, eczema, m\u1ec7t m\u1ecfi.<\/li>\n<li>\u00cdt g\u1eb7p (1\/1000 &lt; ADR &lt; 1\/100): Rung nh\u0129.<\/li>\n<li>Hi\u1ebfm g\u1eb7p (1\/10.000 \u2264 ADR &lt; 1\/1000): Suy t\u1ee7y x\u01b0\u01a1ng, thi\u1ebfu m\u00e1u n\u1eb7ng, gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u, t\u0103ng b\u1ea1ch c\u1ea7u eosin, tr\u1ea7m c\u1ea3m, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i vi, gi\u1ea3m t\u1ea7m nh\u00ecn, vi\u00eam t\u1ee5y, vi\u00eam ru\u1ed9t th\u1eeba, v\u00e0ng da \u1ee9 m\u1eadt, vi\u00eam gan, s\u1ecfi m\u1eadt, vi\u00eam t\u00fai m\u1eadt, ph\u00f9 m\u1ea1ch, ti\u00eau c\u01a1 v\u00e2n, b\u1ec7nh c\u01a1, vi\u00eam c\u01a1, r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf HMG-CoA reductase (Statin): T\u0103ng nguy c\u01a1 ti\u00eau c\u01a1 v\u00e2n.<\/li>\n<li>Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng (v\u00ed d\u1ee5 Warfarin): Gemfibrozil l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng, t\u0103ng nguy c\u01a1 xu\u1ea5t huy\u1ebft. C\u1ea7n gi\u1ea3m li\u1ec1u thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng v\u00e0 theo d\u00f5i th\u1eddi gian prothrombin \u0111\u1ecbnh k\u1ef3.<\/li>\n<li>C\u01a1 ch\u1ea5t c\u1ee7a CYP2C8 (v\u00ed d\u1ee5: Repaglinid, Pioglitazon): Gemfibrozil \u1ee9c ch\u1ebf CYP2C8, l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u00e1c thu\u1ed1c n\u00e0y. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh ph\u1ed1i h\u1ee3p v\u1edbi Repaglinid.<\/li>\n<li>C\u01a1 ch\u1ea5t c\u1ee7a OATP-1B1 (v\u00ed d\u1ee5: Atorvastatin, Rosuvastatin): Gemfibrozil \u1ee9c ch\u1ebf OATP-1B1, l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u00e1c thu\u1ed1c n\u00e0y.<\/li>\n<li>Nh\u1ef1a g\u1eafn acid m\u1eadt (v\u00ed d\u1ee5: Colestipol): Gi\u1ea3m h\u1ea5p thu Gemfibrozil. N\u00ean d\u00f9ng c\u00e1ch nhau 2 gi\u1edd ho\u1eb7c h\u01a1n.<\/li>\n<li>Colchicin: T\u0103ng nguy c\u01a1 ti\u00eau c\u01a1 khi d\u00f9ng \u0111\u1ed3ng th\u1eddi. Th\u1eadn tr\u1ecdng \u1edf ng\u01b0\u1eddi cao tu\u1ed5i v\u00e0 suy th\u1eadn.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng do ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, hoa m\u1eaft, gi\u1ea3m t\u1ea7m nh\u00ecn, c\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n t\u1ea1i, kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho qu\u00e1 li\u1ec1u Gemfibrozil. Vi\u1ec7c x\u1eed tr\u00ed ch\u1ee7 y\u1ebfu t\u1eadp trung v\u00e0o \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Aleksi Tornio, Pertti J Neuvonen, Mikko Niemi, Janne T Backman. Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters, truy c\u1eadp ng\u00e0y 14 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27548563\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27548563\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Savi Gemfibrozil 600 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Savi, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110293923 (VD-28033-17), \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n lipid m\u00e1u h\u1ed7n h\u1ee3p.<\/p>\n","protected":false},"author":1,"featured_media":123481,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-123476","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product\/123476","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/comments?post=123476"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/media\/123481"}],"wp:attachment":[{"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/media?parent=123476"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product_cat?post=123476"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/hmm88i.com\/drug\/wp-json\/wp\/v2\/product_tag?post=123476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}